Phytocannabinoid
THCV (Tetrahydrocannabivarin)
THCV, or tetrahydrocannabivarin, is a minor cannabinoid structurally similar to THC but with distinct effects. At low doses THCV behaves as a CB1 antagonist (reducing rather than producing intoxication), while at higher doses it becomes a CB1 agonist. THCV is associated with appetite suppression — uncommon among cannabinoids.
Associated effects
appetite suppression, biphasic CB1 activity
THCV is one of the more pharmacologically interesting cannabinoids. At low doses (under 10 mg) it behaves as a CB1 receptor antagonist, which counterintuitively means it reduces some of the effects of THC rather than producing them. At higher doses it crosses over to become a CB1 agonist similar to THC. THCV is also associated with appetite suppression — opposite to THC's appetite stimulation — and has received research attention as a potential weight-management compound.
Related cannabinoids
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